Huntingtons disease biography of christopher

“It’s only when the repeat becomes extremely long that it begins to cause harm,” said co-senior author Steve McCarroll, an institute member and director of genomic neurobiology at the Stanley Center for Psychiatric Research at the Broad Institute, the Dorothy and Milton Flier Professor of Biomedical Science and Genetics in the Blavatnik Institute at HMS, and an investigator of the Howard Hughes Medical Institute.

“This is a really different way of thinking not only about how Huntington’s disease develops but also about how a mutation brings about a disease. We think that it will apply in DNA-repeat disorders beyond Huntington’s disease.”

The findings also suggest avenues researchers could pursue to delay or even prevent Huntington’s.

For instance, candidate Huntington’s drugs that aim to reduce activity of the mutated gene (or the protein it codes for) have struggled in clinical trials.

The new study implies