Huntingtons disease biography of christopher
Huntington disease (HD), a neurodegenerative autosomal dominant disorder, is characterized by involuntary choreatic movements with cognitive and behavioral disturbances. It occurs as a result of cytosine, adenine, and guanine (CAG) trinucleotide repeats on the short arm of chromosome 4p in the Huntingtin (HTT) gene. This mutation leads to an abnormally long expansion of the polyglutamine.